V. A. Safonov1, M. Alhamed2, A. E. Chernitskiy3
1Voronezh State Agricultural University named after Emperor Peter the Great, ul. Michurina, 1, Voronezh, 394087, Russian Federation
2Voronezh State University, Universitetskaya pl., 1, Voronezh, 394018, Russian Federation
3All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy, ul. Lomonosova, 114b, Voronezh, 394087, Russian Federation
Abstract. he purpose of the research was to study the effect of endogenous intoxication (EI) in pregnant cows on colostrum composition in the first milk yield and offspring viability. Blood for research was taken from the cows of the Red-Motley breed (n = 43) 30–37 days before calving; colostrum was taken in 30 minutes after calving; calves’ blood was taken 24 hours after birth. The EI level in cows was determined by the content of medium molecular weight peptides (MMP) in the blood serum: 0.200–0.400 conv. units (the first group, n = 20); 0.401–0.600 conv. units (the second group, n = 13); 0.601–0.800 conv. units (the third group, n = 10). The significance of differences between groups was assessed using the U-test of Mann and Whitney for independent variables; the relationship between the variables was determined by Spearman’s correlation coefficient. In the colostrum of cows from the second and third groups, we found a decrease in the concentration of vitamin E (by 26.4–42.7%, p was less than 0.05), cortisol (by 43.2–62.6%, p was less than 0.05), estradiol (by 70.4%, p was less than 0.05), the binding capacity of casein and albumin (by 27.4–45.7%, p was less than 0.05), an increase in progesterone (by 69.4%, p was less than 0.05), the level of MMP (by 14.1–57.0%, p was less than 0.05) and intoxication coefficient (by 38.9–126.0%, p was less than 0.05), compared with the first group. The content of protein and total immunoglobulins as well as density and titratable acidity did not change significantly. In newborn calves from the second and third groups, we registered a decreased muscle tone; the content of erythrocytes in the blood also decreased by 11.0% (p was less than 0.05); the content of haemoglobin decreased by 11.6–12.7% (p was less than 0.05), the content of hematocrit decreased by 13.1–14.8% (p was less than 0.05); the number of platelets increased by 16.1–28.8% (p was less than 0.05); the number of neutrophils increased by 55.0–80.0% (p was less than 0.05); the cortisol/dehydroepiandrosterone sulphate ratio in the serum was more than 2.0, indicating a deterioration in their viability.
Keywords: cow; pregnancy; endogenous intoxication; medium molecular weight peptides; calves; colostrum; viability.
Author Details: V. A. Safonov, D. Sc. (Biol.), professor (e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра.); M. Alhamed, post graduate student (e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра.); A. E. Chernitskiy, D. Sc. (Biol.), senior researcher (e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра.).
For citation: Safonov VA, Alhamed M, Chernitskiy AE. [Influence of endogenous intoxication in pregnant cows on colostrum quality and offspring viability]. Dostizheniya nauki i tekhniki APK. 2021;35(4):50-5. Russian. doi: 10.24411/0235-2451-2021-10408.