M. A. Eryomina1, I. Yu. Ezdakova2
1Federal Scientific Center of Animal Husbandry – L.K. Ernst All-Russian Research Institute of Animal Husbandry, pos. Dubrovitsy, 60, Podol’skii r-n, Moskovskaya obl., 142132, Russian Federation
2Kovalenko All-Russia Research Institute of Experimental Veterinary, Ryazanskii Prospect, 24/1, Moscow, 109428, Russian Federation
Abstract. It was studied the regularities of the functioning of the immune system of cows of different genetic and immunologic groups on the basis of the determination of diagnostic landmarks of immunocompetence. The surveys were carried out in the Lukoshkino farm (Moscow) in 2016–2017 with Holstein cows, the daughters of 11 bulls, previously grouped according to the IgG content in spring and autumn. According to the results of analysis of variance, the level of IgG variation was defined as stable if it was from 24.1to 29.0 mg/ mL (n = 7 heads), and it was defined as unstable if it was from 18.0 to 26.3 mg/ mL (n = 4 heads). Further, the daughters of these bulls were grouped: I – 16 heads, II – 18 heads. To determine the IgG content using simple radial immunodiffusion and cellular immunity factors, blood samples were taken from cows in the spring-summer and autumn-winter periods. Functional interrelations were studied with the help of correlation analysis between cellular immunity factors. In the second group, the IgG content significantly increased in the autumn-winter period, compared with the spring-summer period (28.3 and 26.5 mg/mL, respectively), and the phagocytic activity decreased, in relation to the lower limit of the norm (32.3 and 48.0% respectively). In cows of both groups in winter, the number of reliable correlation links between the cellular components of the blood was equal to 2. In the spring in the first group, the neutrophil/eosinophilic connections (-0.446) and the phagocytic activity/eosinophils (-0.450) added to the neutrophil/lymphocyte connection (-0.563). In group II during this period, the number of reliable correlations was 5: IgG/phagocytic activity (0.480); neutrophils/lymphocytes (-0.674); lymphocytes/monocytes (-0.772); lymphocytes/phagocytic activity (0.521); monocytes/phagocytic activity (-0.528). In cows-daughters of bulls with unstable genetic and immunological indicators, the load on the immune system in the spring was higher, as the increased number of correlation links serves as a sign of the functional stress of the immune system, its instability and the nonequilibrium state.
Keywords: cows; bulls; genotype; alleles; immunoglobulins; neutrophils; basophils; monocytes; phagocytic activity; differential blood cell count; immune activity; correlation; population.
Author Details: M. A. Eryomina, D. Sc. (Agr.), senior research fellow (e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра.); I. Yu. Ezdakova, D. Sc. (Biol.), head of laboratory (e-mail: Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра.).
For citation: Eryomina M. A., Ezdakova I. Yu. Indices of Immunoreactivity of Cows, Daughters of Bulls of Different Genetic and Immunologic Groups. Dostizheniya nauki i tekhniki APK. 2018. Vol. 32. No. 4. Pp. 50-53 (in Russ.). DOI: 10.24411/0235-2451-2018-10412.